Research focus

How oscillations shape the functional architecture of the working brain
The 'Neuronal Oscillations' research group is part of the newly established Centre for Human Brain Health at University of Birmingham. It is headed by Prof. Ole JensenWolfson Research Merit Award holder. The group is funded by a Wellcome Trust Senior Investigator award, the James S. McDonnell Foundation and several EU Horizon 2020 Marie Curie fellowships. 


The main goal of the 'Neuronal Oscillations' research group is to understand how oscillatory activity shapes the functional architecture of the working brain during cognitive processing. While modulations of alpha band oscillations (8-13 Hz) reflect anticipatory top-down modulation, bottom-up processing is reflected by gamma band synchronization (30-100 Hz). Specifically, our core
 hypothesize states that neuronal communication is gated by inhibitory alpha oscillations in task-irrelevant regions, thus routing information to task-relevant regions. According to this framework the brain can be studied as a network by investigating cross-frequency interactions between gamma and alpha activity. The research tools applied by the group include computational modeling, MEG
EEG combined with fMRI, EEG combined with TMS and intracranial recordings. These tools are applied to investigate and interpret data from humans and animals performing 
attention and memory tasks. Furthermore, we investigate these mechanism to understand the basis of attention problems in ADHD patients and the aging population. 

News

  • Paper accepted Biol Psychiatry Lenartowicz, A., Mazaheri, A., Jensen, O. and Loo, S.K. (accepted) Aberrant modulation of brain oscillatory activity and attentional impairment in ADHD. Biol Psychiatry
    Posted Sep 17, 2017, 10:55 PM by Ole Jensen
  • Paper accepted in Behav Brain Res Noonan, M., Crittenden, B., Jensen, O., and Stokes, M. (accepted) Selective inhibition of distracting input. Behav Brain Res
    Posted Sep 2, 2017, 11:53 PM by Ole Jensen
  • Paper accepted in J Cogn Neurosci Lin, W., Hagoort, P., and Jensen, O. (accepted)  Language prediction is supported by coupling between frontal gamma and posterior alpha oscillations. J Cogn Neurosci
    Posted Aug 28, 2017, 9:24 PM by Ole Jensen
  • Paper accepted in J Cogn Neurosci Marshall, T.R., den Boer, S., Cools, R., Jensen, O., Fallon, S.J., and Zumer, J.M. (in press) Alpha and gamma oscillations support complementary mechanisms for processing stimulus value associations. J Cogn Neurosci
    Posted Aug 16, 2017, 8:10 AM by Ole Jensen
  • Ole Jensen receives Wellcome Trust Investigator Award 5 years of funding to study phase coding in the visual system
    Posted Jul 17, 2017, 11:39 PM by Ole Jensen
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Background information:

Opinion: Jensen, O., Gips, B., Bergmann, T.O. and Bonnefond, M. (2014) Temporal coding organized by coupled alpha and gamma oscillations prioritize visual processing. Trends in Neurosciences

Review: Lisman, J.E and Jensen, O. (2013) The theta-gamma neural code. Neuron 77:1002-1016. 

Review: Jensen, O. and Mazaheri, A. (2010) Shaping functional architecture by oscillatory alpha activity: gating by inhibition. Front Hum Neurosci 4:186. 

Weekly events

Group meeting
Neuosc Group. Wednesdays 11 am

Discussion clubs
System neuroscience journal club. Mondays 11 am